Treatment with Evrysdi (risdiplam) may modestly improve arm function for adults with spinal muscular atrophy (SMA), a new study indicates.
Understanding how microscopic interactions between proteins in cells produce large-scale organization and asymmetry is a fundamental question in cell biology.
Cells all require the transport of materials to maintain their function. In nerve cells, a tiny motor made of protein called KIF1A is responsible for that. Mutations in this protein can lead to ...
The framework predicts how proteins will function with several interacting mutations and finds combinations that work well ...
Summary of this study. Left: Normal cells. Second from left: Cells with slightly reduced CENP-E function. These cells show slightly delayed chromosome alignment but remain viable before KIF18A ...
A human heart might contract some three billion times over a lifetime, and each one of those contractions is driven by a protein called myosin. One of three classes of so-called motor proteins in our ...
Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...